THE BLOCKING SOLUTION

화학적으로 변형되고 조각난 고순도 카제인 기반 차단제

Casein based blocker for minimizing nonspecific binding to surfaces. 

The Blocking Solution saturates free binding sites on plastic surfaces, membranes or other protein binding surfaces and prevents nonspecific binding to surfaces. 

This minimizes unwanted binding of the analyte or the detection antibody to the surface and so background can be avoided and sensitivity of the assay can be improved. 

Additionally, no components of the sample can bind nonspecifically to the surface, if it is effectively blocked. 

The Blocking Solution is based on chemically modified and fragmented highly purified casein.

The production process of The Blocking Solution has been developed and up-scaled by CANDOR. This proprietary process guarantees an extremely good lot-to-lot consistency which can normally be obtained only from synthetic raw materials although the casein is derived originally from natural sources.

Decrease of the coefficient of variation. Compared to standard blockers, The Blocking Solution impressively lowered the coefficient of variation as shown in this assay validation of a competitive ELISA (n = 96, measured at the maximum B0).

The Blocking Solution is routinely used as a blocker in industrial scale production of immunodiagnostics by several international kit manufacturers.

The Blocking Solution is not comparable to other commercially avail - able or home-made casein based solutions which are produced by just dissolving and filtration of casein. 

SMARTBLOCK

펩타이드 기반의 BSA-free 차단제

BSA-free blocker for saturating free binding sites on plastic surfaces or other protein binding surfaces. 

SmartBlock™ is a modern blocker based on peptides. To further improve the blocking efficiency, peptides were chemically modified in a specific process. The result is a peptide solution with very good blocking characteristics. At the same time SmartBlock™ has a very good lot-to-lot consistency, up until now obtained only by synthetic blockers.

SmartBlock™ sets standards in the development of economically priced assays with good reliability e.g. for diagnostics, pharmaceutical research, pharmaceutical or biotechnological process control, food diagnostics, environmental diagnostics or research.

For many assays SmartBlock™ is an economical and useful alternative to BSA containing solutions.

BSA-BLOCK

Standard blocker for saturating free binding sites on plastic surfaces or other protein binding surfaces. 

BSA-Block is a well-established, versatile blocker for many applications.

The high purity and control of the raw materials enable good lot-to-lot consistency for this blocker based on BSA.

Therefore a high reliability of the assay over years is obtained even when different lots are used.

If you experience background due to nonspecific binding even when using BSA-Block, we recommend using The Blocking Solution.